BiochemistrybioRxiv
Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation
K. Brown, P. Y. Chew, S. Ingersoll…·X. Ren
This study reveals the scaffold-client model of PRC1 condensate assembly through phase separation, showing how CBX2 acts as a scaffold and other subunits influence condensate properties and composition.
DOI 10.1016/j.celrep.2023.113136