ImmunologybioRxiv
Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22
D. Schnepf, P. Hernandez, T. Mahlakoiv…·P. Staeheli
This study shows that antibiotic-treated mice are more susceptible to rotavirus due to reduced IL-22 expression, which normally inhibits viral replication through mechanisms independent of IFN signaling.
DOI 10.1371/journal.pone.0247738