BiochemistrybioRxiv
Development of a PNGase Rc column for online deglycosylation of complex glycoproteins during HDX-MS
T. O. T. Lambert, M. Gramlich, L. S. Stutzke…·K. D. Rand
The paper develops a PNGase Rc column for online deglycosylation during HDX-MS, enabling efficient analysis of glycoproteins and mapping of mAb binding epitopes.
DOI 10.1021/jasms.3c00268