Cancer BiologybioRxivPreprint
HDAC6 promotes self-renewal and migration/invasion of rhabdomyosarcoma
E. Chen, T. Q. Pham, K. Robinson…·S. X. Skapek
This study identifies HDAC6 as a driver of RMS tumor growth, self-renewal, and migration/invasion, with RAC1 as a key mediator, suggesting targeting the HDAC6-RAC1 axis as a therapeutic strategy.