Author

T. Rustad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Sherman· 2 shared C. Levine· 1 shared D. Alland· 1 shared F. Mast· 1 shared H. Safi· 1 shared H.-P. H. Liang· 1 shared J. D. Aitchison· 1 shared L. Blanc· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

D. Sherman

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2 papers

Recent·Most cited

ODELAM: Rapid sequence-independent detection of drug resistance in clinical isolates of Mycobacterium tuberculosis

T. Herricks, M. Donczew, F. Mast, T. Rustad, R. Morrison, T. R. Sterling, D. Sherman, J. D. Aitchison

ODELAM rapidly detects drug resistance in Mtb clinical isolates using time-lapse microscopy, identifying ofloxacin resistance and heteroresistance in 48 hours.

bioRxiv · Mar 17, 2020Microbiology

Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance

H. Safi, P. Gopal, S. Lingaraju, S. Ma, C. Levine, V. Dartois, M. Yee, L. Li, L. Blanc, H.-P. H. Liang, S. Husain, M. Hoque, P. Soteropoulos, T. Rustad, D. Sherman, , D. Alland

This paper identifies a novel mechanism of drug tolerance in M. tuberculosis through phase variation in the glpK gene, showing reversible frameshift mutations that contribute to treatment failure and relapse.

bioRxiv · Jul 30, 2019Microbiology