M. Yee

BROADLY NEUTRALIZING ANTI- HIV-1 ANTIBODIES DO NOT INHIBIT HIV-1 ENV-MEDIATED CELL-CELL FUSION

This study shows that broadly neutralizing HIV-1 antibodies do not inhibit Env-mediated cell-cell fusion, suggesting they may not prevent viral transmission via this route.

Low Dose Hyperoxia Primes Airways for Fibrosis in Mice after Influenza A Infection

The paper shows low-dose neonatal hyperoxia increases TSP-1 expression in mice, which primes lungs for fibrosis after influenza A infection, even when lung function appears normal.

Pyrazinamide triggers degradation of its target aspartate decarboxylase

This paper shows that pyrazinamide's active form, POA, triggers degradation of its target enzyme PanD via the ClpC1-ClpP protease, rather than inhibiting it directly.

Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance

This paper identifies a novel mechanism of drug tolerance in M. tuberculosis through phase variation in the glpK gene, showing reversible frameshift mutations that contribute to treatment failure and relapse.