ImmunologybioRxivPreprint
The SARS-CoV-2 Omicron BA.1 spike G446S potentiates HLA-A*24:02-restricted T cell immunity
DOI 10.1101/2022.04.17.488095
Author
T. S. Tan
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2021-2022 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 44 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- MicrobiologybioRxiv
SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant
I. Kimura, D. Yamasoba, H. Nasser…·K. Sato
This study identifies the S375F mutation in the Omicron spike protein as responsible for its reduced cleavage efficiency, fusogenicity, and rapid spread.
DOI 10.1016/j.isci.2022.105720 - MicrobiologybioRxiv
SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion
B. Meng, I. Ferreira, A. Abdullahi…·S. Zepeda
This study investigates the immune escape, infectivity, and cell-cell fusion properties of SARS-CoV-2 Omicron BA.1 compared to Delta, showing higher ACE2 affinity and antibody evasion but similar antiviral drug efficacy.
DOI 10.1038/s41586-022-04474-x - MicrobiologybioRxiv
An emerging SARS-CoV-2 mutant evading cellular immunity and increasing viral infectivity
C. Motozono, M. Toyoda, J. Zahradnik…·K. Sato
This study identifies two SARS-CoV-2 mutations, L452R and Y453F, that evade HLA-restricted cellular immunity and increase viral infectivity.
DOI 10.1016/j.chom.2021.06.006 - MicrobiologyNature CommunicationsPeer-reviewed
Naturally mutated spike proteins of SARS-CoV-2 variants show differential levels of cell entry
S. Ozono, Y. Zhang, H. Ode…·K. Tokunaga
The paper examines how naturally occurring mutations in SARS-CoV-2 spike proteins affect cell entry via ACE2 and TMPRSS2, finding that the D614G mutation increases infectivity but remains neutralization-sensitive.
DOI 10.1038/s41467-021-21118-2