BioengineeringbioRxiv
An engineered monomer binding-protein for α-synucleinefficiently inhibits the proliferation of amyloid fibrils
E. D. Agerschou, T. Saridaki, P. Flagmeier…·A. K. Buell
The paper engineers a monomer-binding protein that inhibits α-synuclein fibril proliferation in vitro and in vivo, showing it reduces aggregates and related pathologies.