Author

P. Flagmeier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bruzas· 1 shared A. K. Buell· 1 shared A. Nagpal· 1 shared A. Vilalta· 1 shared A. Voigt· 1 shared B. H. Falkenburger· 1 shared C. Galvagnion· 1 shared C. M. Dobson· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Bruzas

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer's R47H mutant does the opposite

A. Vilalta, Y. Zhou, J. Sevalle, J. K. Griffin, K. Sato, D. H. Allendorf, S. De, M. Puigdellivol, A. Bruzas, M. A. Burguillos, R. B. Dodd, F. Chen, Y. Zhang, P. Flagmeier, L.-M. Needham, , G. C. Brown

The paper shows wild-type sTREM2 inhibits Aβ aggregation and neurotoxicity, while the R47H variant promotes Aβ aggregation and neurotoxicity.

bioRxiv · Dec 3, 2020Biochemistry

An engineered monomer binding-protein for α-synucleinefficiently inhibits the proliferation of amyloid fibrils

E. D. Agerschou, T. Saridaki, P. Flagmeier, C. Galvagnion, D. Komnig, A. Nagpal, N. Gasterich, L. Heid, V. Prasad, H. Shaykhalishahi, A. Voigt, D. Willbold, C. M. Dobson, B. H. Falkenburger, W. Hoyer, A. K. Buell

The paper engineers a monomer-binding protein that inhibits α-synuclein fibril proliferation in vitro and in vivo, showing it reduces aggregates and related pathologies.

bioRxiv · Mar 5, 2019Bioengineering