Author

T. Ulven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Tobin· 2 shared G. Milligan· 2 shared A. G. Alharbi· 1 shared A. Manandhar· 1 shared B. D. Hudson· 1 shared C. Donovan· 1 shared C. E. Brightling· 1 shared C. H. Wiegman· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. B. Tobin

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3 papers

Recent·Most cited

The two formyl peptide receptors differently regulate GPR84-mediated neutrophil NADPH-oxidase activity

J. Martensson, M. Sundqvist, A. Manandhar, L. Ieremias, L. Linjie, T. Ulven, X. Xie, L. Bjorkman, H. Forsman

This study shows that FPR1 and FPR2 differentially regulate GPR84-mediated neutrophil NADPH-oxidase activity, with FPR2 reactivation amplifying ROS production and FPR1 suppressing it.

bioRxiv · Nov 13, 2020Immunology

Pathophysiological regulation of lung function by the free fatty acid receptor FFA4

A. B. Tobin, R. Prihandoko, D. Kaur, C. H. Wiegman, E. Alvarez-Curto, C. Donovan, L. Chachi, T. Ulven, M. R. Tyas, E. Euston, Z. Dong, A. G. Alharbi, R. Kim, J. G. Lowe, P. M. Hansbro, , G. Milligan

This study shows that activating FFA4 reduces airway resistance in mouse models of inflammation and human lung tissue, suggesting it could be a therapeutic target for asthma and COPD.

bioRxiv · May 18, 2020Pharmacology & Toxicology

Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis

A. B. Tobin, N. Barki, D. Bolognini, U. Borjesson, L. Jenkins, J. Riddell, D. I. Hughes, T. Ulven, B. D. Hudson, E. R. Ulven, N. Dekker, G. Milligan

This study identifies a specific agonist for a modified FFA2 receptor and demonstrates distinct roles of FFA2 and FFA3 in gut-brain communication using genetically engineered mice.

bioRxiv · Jan 11, 2020Pharmacology & Toxicology