Cancer BiologybioRxivPreprint
Discovery of a novel human antibody VH domain with potent activity against mesothelin expressing cancer cells in both CAR T-cell and antibody drug conjugate formats
Z. Sun, X. Chu, C. Adams…·D. S. Dimitrov
The paper identifies a novel human antibody VH domain with high affinity for mesothelin and demonstrates its efficacy in both CAR-T cell and antibody drug conjugate formats against mesothelin-expressing cancer cells.
DOI 10.1101/2022.04.07.487497