MicrobiologybioRxiv
Bacterial pore-forming toxin pneumolysin drives pathogenicity through shed toxin-loaded host extracellular vesicles
S. Parveen, C. V. Bhat, S. Aziz…·K. Subramanian
This study shows that pneumolysin-loaded host extracellular vesicles contribute to pneumococcal pathogenesis by inducing cytotoxicity and inflammation.