Author

V. D. Jonsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Aguilar· 1 shared B. Badie· 1 shared B. C. Bastian· 1 shared B. S. Taylor· 1 shared C. E. Brown· 1 shared C. M. Blakely· 1 shared C. Martinez· 1 shared D. Alizadeh· 1 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

B. Aguilar

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Author profile →

3 papers

Recent·Most cited

PD-L1 blockade restores CAR T cell activity through IFNγ-regulation of CD163+ macrophages

Y. Yamaguchi, J. Gibson, K. Ou, R. H. Ng, V. D. Jonsson, J. C. Zarif, P. P. Lee, X. Wang, C. Martinez, T. B. Dorff, S. J. Forman, S. J. Priceman

This study shows that PD-L1 blockade enhances CAR T cell activity by altering macrophage phenotypes through IFNγ signaling in the tumor microenvironment.

bioRxiv · Jan 25, 2022 · PreprintImmunology

CAR T cell therapy drives endogenous locoregional T cell dynamics in a responding patient with glioblastoma

V. D. Jonsson, R. Ng, N. Dullerud, R. A. Wong, J. Hibbard, D. Wang, B. Aguilar, R. Starr, L. Weng, D. Alizadeh, S. Forman, B. Badie, C. E. Brown

This study tracks T cell dynamics in a glioblastoma patient undergoing CAR T cell therapy, showing endogenous T cells are activated and contribute to treatment response.

bioRxiv · Sep 22, 2021 · PreprintImmunology

Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution

V. D. Jonsson, C. M. Blakely, L. Lin, S. Asthana, V. Olivas, M. A. Gubens, N. Matni, B. C. Bastian, B. S. Taylor, J. C. Doyle, T. G. Bivona

This paper develops a computational framework to predict dynamic polytherapy switching strategies to address tumor heterogeneity and evolution in lung adenocarcinoma.

bioRxiv · Nov 8, 2016Cancer Biology