S. Asthana

The paper shows that SARS-CoV-2 spike antibodies can enhance DENV2 infection in vitro and in vivo, suggesting potential for increased dengue severity in COVID-19 survivors.

The paper uses molecular dynamics simulations to study conformational changes in a nicotinic receptor site induced by agonists, identifying key steps in the low-to-high affinity transition.

This study investigates how SDS and CTAB detergents affect the structure of peanut agglutinin using spectroscopic and molecular dynamics simulations, revealing structural perturbations and conformational changes.

This study investigates how oxysterols impair CXCR4 signaling by disrupting cholesterol-protein interactions and altering signaling residue conformations.

This study identifies the RNA-protein interactome of the Hepatitis E virus IRESl element and confirms its function as a bona fide internal ribosome entry site.

The paper identifies dominant immune system archetypes across 364 tumors from 12 cancer types using flow cytometry and transcriptomic data, linking them to tumor biology classifications.

This study shows that SARS-CoV-2 infection in golden Syrian hamsters causes lung and cardiovascular pathologies similar to human COVID-19, suggesting GSH as a model for studying long-term effects.

This paper identifies a direct interaction between JEV capsid protein and non-lipidated MAP1LC3 on replication membranes and lipid droplets, independent of p62/SQSTM1.

The paper identifies PDHK1 as a synthetic-essential gene in PTEN-deficient cells and cancers, showing its upregulation drives aerobic glycolysis and correlates with poor patient survival.

This paper develops a computational framework to predict dynamic polytherapy switching strategies to address tumor heterogeneity and evolution in lung adenocarcinoma.