Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia
G. Qin, J. Dai, S. Chien…·P. S. Becker
The paper identifies mutation patterns linked to drug sensitivity in AML using integrated computational and experimental analysis.
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5 papers
Recent·Most cited
G. Qin, J. Dai, S. Chien…·P. S. Becker
The paper identifies mutation patterns linked to drug sensitivity in AML using integrated computational and experimental analysis.
R. Starr, X. Yang, B. Aguilar…·C. E. Brown
This study compares IL13-ligand CAR designs to determine how co-stimulation domains affect tumor selectivity and anti-tumor activity against glioblastoma.
V. D. Jonsson, R. Ng, N. Dullerud…·C. E. Brown
This study tracks T cell dynamics in a glioblastoma patient undergoing CAR T cell therapy, showing endogenous T cells are activated and contribute to treatment response.
D. Wang, R. Starr, W.-C. Chang…·C. Brown
This study develops a CAR T cell therapy using chlorotoxin to target glioblastoma with high specificity and potency, overcoming tumor heterogeneity challenges.