Author

V. Molodtsov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:E. coli· 1

Frequent Co-Authors

R. H. Ebright· 2 shared A. Renda· 1 shared A. Tareen· 1 shared B. E. Nickels· 1 shared C. Pukhrambam· 1 shared H. Vu· 1 shared J. B. Kinney· 1 shared J. T. Winkelman· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

R. H. Ebright

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Structural and mechanistic basis of σ-dependent transcriptional pausing

C. Pukhrambam, V. Molodtsov, M. Kooshkbaghi, A. Tareen, H. Vu, K. S. Skalenko, M. Su, Y. Zhou, J. T. Winkelman, J. B. Kinney, R. H. Ebright, B. E. Nickels

This paper identifies the structural basis of σ-dependent transcriptional pausing by showing that it involves backtracked or scrunched states of RNA polymerase, depending on the presence of GreB.

bioRxiv · Jan 24, 2022Biochemistry

Structural basis of RNA polymerase recycling by the Swi2/Snf2 ATPase RapA in Escherichia coli

M. Z. Qayyum, V. Molodtsov, A. Renda, K. S. Murakami

The paper determines cryo-EM structures of E. coli RapA-RNAP complexes to elucidate how RapA prevents RNAP from non-specific DNA binding, enhancing RNAP recycling after transcription termination.

bioRxiv · May 5, 2021Biochemistry

RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription

L. Li, V. Molodtsov, W. Lin, R. H. Ebright, Y. Zhang

This paper reports crystal structures showing the stepwise displacement of the σ finger in bacterial transcription initiation factors driven by RNA extension during initial transcription.

bioRxiv · Nov 26, 2019Biochemistry