Author

H. Vu

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Organism:multiple species· 2

Frequent Co-Authors

A ArnesoniD· 1 shared A. Arneson· 1 shared A. Caulton· 1 shared A. D. Rao· 1 shared A. Haghani· 1 shared A. J. Jasinska· 1 shared A. J. Levine· 1 shared A. K. L. Leung· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperDevelopmental Biology

A ArnesonORCID

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Author profile →

5 papers

Recent·Most cited

Interferon-Induced PARP14-Mediated ADP-Ribosylation in p62 Bodies Requires an Active Ubiquitin-Proteasome System

R. Raja, B. Biswas, R. Abraham, H. Liu, C.-Y. Chang, H. Vu, A. K. L. Leung

This study shows interferon induces ADP-ribosylation in p62 bodies via PARP14, requiring ubiquitin activation and proteasome activity.

bioRxiv · May 22, 2024 · PreprintCell Biology

Universal DNA methylation age across mammalian tissues

Ake Tzu-Hui Lu, Zhe Fei, Amin Haghani, Todd R. Robeck, Joseph Alan Zoller, Caesar Z. Li, Robert Lowe, Qi Jiang Yan, Joshua Zhang, H. Vu, Julia Ablaeva, Victoria A. Acosta-Rodríguez, Danielle M. Adams, Javier Almunia, Ajoy Aloysius, , June Mergl

The paper develops universal epigenetic clocks that accurately estimate age across mammalian tissues using DNA methylation data from 185 species.

Nature Aging · Aug 10, 2023Peer-reviewedDevelopmental Biology

In-vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma

A. Kaushik, L. K. Burroughs, A. Tarangelo, M. Ragavan, C.-Y. Wu, X. Li, K. Ahumada, V. T. Tcheuyap, F. Saatchi, Q. Do, C. Yong, T. Rosales, C. Stevens, A. D. Rao, B. Faubert, , R. J. DeBerardinis

The paper identifies multiple glutamine metabolism pathways in ccRCC tumorgrafts and shows that targeting amidotransferase activity reduces tumor growth.

bioRxiv · Oct 31, 2022Cancer Biology

Structural and mechanistic basis of σ-dependent transcriptional pausing

C. Pukhrambam, V. Molodtsov, M. Kooshkbaghi, A. Tareen, H. Vu, K. S. Skalenko, M. Su, Y. Zhou, J. T. Winkelman, J. B. Kinney, R. H. Ebright, B. E. Nickels

This paper identifies the structural basis of σ-dependent transcriptional pausing by showing that it involves backtracked or scrunched states of RNA polymerase, depending on the presence of GreB.

bioRxiv · Jan 24, 2022Biochemistry

Epigenetic predictors of maximum lifespan and other life history traits in mammals

C. Z. Li, A. Haghani, T. R. Robeck, D. Villar, A. T. Lu, J. Zhang, C. G. Faulkes, H. Vu, J. Ablaeva, D. M. Adams, R. Ardehali, A. Arneson, C. S. Baker, K. Belov, D. T. Blumstein, , A. J. Jasinska

The paper develops methylation-based models to predict maximum lifespan and other life history traits in mammals using data from 12,000 samples across 192 species.

bioRxiv · May 16, 2021 · PreprintEvolutionary Biology