V. P. Bykerk

This study uses single-cell antigen receptor profiling to identify clonal relationships and functional states of T and B cells in RA synovium.

The paper identifies key inflammatory cell states in RA synovial tissues using integrated single-cell and mass cytometry data from patient samples.

This paper establishes a protocol for dissociating cryopreserved synovial tissue to obtain viable cells with preserved transcriptomes and surface markers, enabling high-dimensional analysis of rheumatoid arthritis pathology.

The paper identifies disease-associated fibroblast subsets in rheumatoid arthritis using single-cell transcriptomics and flow cytometry, revealing subset-specific markers and functional differences.