Author

V. Reddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Akbar· 1 shared A. Huebner· 1 shared A. Iskander· 1 shared A. U. Akarca· 1 shared B. Behr· 1 shared B. Neuman· 1 shared C. Gawad· 1 shared C. Hwang· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCancer Biology

A. Akbar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease

K. Khatua, Y. R. Alugubelli, K. Yang, V. Reddy, L. Blankenship, D. Coleman, S. Atla, S. Chaki, Z. Geng, X. Ma, J. Xiao, P.-H. Chen, C.-C. Cho, E. C. Vatansever, Y. Ma, , W. R. Liu

This study develops an azapeptide platform with covalent warheads to identify potent SARS-CoV-2 MPro inhibitors, including MPI89 with a 10 nM EC50 and high selectivity.

bioRxiv · Apr 11, 2023 · PreprintBiochemistry

Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer

D. R. Pearce, A. U. Akarca, R. P. H. De Maeyer, E. Kostina, A. Huebner, M. Sivakumar, T. Karasaki, K. Shah, S. M. Janes, N. E. McGranahan, V. Reddy, A. Akbar, D. A. Moore, T. Marafioti, C. Swanton, R. E. Hynds

The paper identifies lymphoproliferative B cells in NSCLC PDX models and develops a tool for generating pathology overview figures.

bioRxiv · Jan 24, 2023Cancer Biology

Genome-wide Disease Screening in Early Human Embryos with Primary Template-Directed Amplification

Y. Xia, V. Gonzales-Pena, D. Klein, J. Luquette, L. Puzon, N. Siddiqui, V. Reddy, P. Park, B. Behr, C. Gawad

This paper introduces a method to screen early human embryos for genetic variants using primary template-directed amplification, identifying aneuploidy, mitochondrial variants, and disease-causing mutations, and computing polygenic risk scores.

bioRxiv · Jul 6, 2021 · PreprintBioengineering

Castration-resistant prostate cancer: Androgen receptor inactivation induces telomere DNA damage, and damage response inhibition leads to cell death

V. Reddy, A. Iskander, C. Hwang, G. Divine, M. Menon, E. R. Barrack, G. P.-v. Reddy, S.-H. Kim

This study shows that combining an AR antagonist with an ATM inhibitor induces telomere DNA damage and DDR inhibition, leading to cell death in CRPC cells.

bioRxiv · Jan 9, 2019Cancer Biology