Author

V. Wimmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. J. Kueh· 2 shared A. Strasser· 2 shared K. Brinkmann· 2 shared P. Bouillet· 2 shared A. K. Voss· 1 shared A. R. Delbridge· 1 shared A. Tee· 1 shared C. L. Rowe· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

A. J. Kueh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Relative importance of MCL-1's Anti-Apoptotic versus Non-Apoptotic Functions in vivo

K. Brinkmann, K. McArthur, A. Tee, A. J. Kueh, S. Malelang, V. Wimmer, L. Gibson, C. L. Rowe, P. Arandjelovic, G. Dewson, T. Putoczki, P. Bouillet, N. Fu, T. Thomas, M. J. Herold, , A. Strasser

This study replaces MCL-1 with other anti-apoptotic proteins in mice to determine the relative importance of MCL-1's anti-apoptotic versus non-apoptotic functions in development and physiology.

bioRxiv · Aug 14, 2023 · PreprintCell Biology

Severe dysregulation of TNF expression leads to multiple inflammatory diseases and embryonic death

P. Bouillet, E. Clayer, D. Dalseno, A. J. Kueh, D. Lacey, M. Tsai, E. Carr, V. Wimmer

The paper identifies a new regulatory element in the Tnf 3UTR that cooperates with existing elements to downregulate TNF expression and prevent autoimmune diseases, and shows excessive TNF causes embryonic death.

bioRxiv · May 28, 2020 · PreprintImmunology

BCL-XL is essential for the protection from secondary anemia caused by radiation-induced fatal kidney damage

K. Brinkmann, P. Waring, S. Glaser, V. Wimmer, D. Nhu, L. Whitehead, A. R. Delbridge, G. Lessene, M. Herold, G. L. Kelly, S. Grabow, A. Strasser

The paper shows that BCL-XL protects adult kidneys from radiation-induced damage, leading to secondary anemia, and highlights its importance in cancer therapy combinations.

bioRxiv · Apr 28, 2020 · PreprintPharmacology & Toxicology