Author

M. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Organism:mouse· 2 Assay:scRNA-seq· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Boland· 2 shared J. Milner· 2 shared K. Omilusik· 2 shared A. C. Ching· 1 shared A. D. Delpoux· 1 shared A. Franchet· 1 shared A. Goldrath· 1 shared A. I. Webb· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

B. Boland

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Choline degradation in Paracoccus denitrificans: identification of sources of formaldehyde

T. Parekh, M. Tsai, S. Spiro

The paper identifies formaldehyde sources from choline degradation in Paracoccus denitrificans and shows that flhSR mutants cannot grow on methanol, methylamine, and choline.

bioRxiv · Dec 12, 2023 · PreprintMicrobiology

Drosophila AHR limits tumor growth and stem cell proliferation in the intestine

M. Tsai, J. Sun, C. Alexandre, M. Shapiro, A. Franchet, Y. Li, A. P. Gould, J.-P. Vincent, B. Stockinger, N. L. Diny

This study shows that Spineless, the Drosophila AHR homolog, limits tumor growth and stem cell proliferation in the adult intestine by regulating gene expression and metabolism.

bioRxiv · May 17, 2023 · PreprintCancer Biology

Physiological Substrates and Ontogeny-Specific Expression of the Ubiquitin Ligases MARCH1 and MARCH8

P. Schriek, H. Liu, A. C. Ching, P. Huang, N. Gupta, K. R. Wilson, M. Tsai, Y. Yan, C. F. Macri, L. F. Dagley, G. Infusini, A. I. Webb, H. McWilliam, S. Ishido, J. D. Mintern, J. A. Villadangos

This study identifies MARCH1 and MARCH8 as specialized regulators of CD4+ T cell immunity in distinct cellular compartments by analyzing their substrates and expression in mice.

bioRxiv · Apr 15, 2021Immunology

Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population

J. Milner, H. Nguyen, K. Omilusik, M. Reina-Campos, M. Tsai, C. Toma, A. D. Delpoux, B. Boland, S. M. Hedrick, J. T. Chang, A. W. Goldrath

This study identifies a terminally differentiated effector memory CD8 T cell population with unique molecular and functional properties that challenge classical definitions of effector memory cells.

bioRxiv · Jul 17, 2020Immunology

Severe dysregulation of TNF expression leads to multiple inflammatory diseases and embryonic death

P. Bouillet, E. Clayer, D. Dalseno, A. J. Kueh, D. Lacey, M. Tsai, E. Carr, V. Wimmer

The paper identifies a new regulatory element in the Tnf 3UTR that cooperates with existing elements to downregulate TNF expression and prevent autoimmune diseases, and shows excessive TNF causes embryonic death.

bioRxiv · May 28, 2020 · PreprintImmunology

Molecular determinants and heterogeneity of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing

N. Kurd, Z. He, J. Milner, K. Omilusik, T. Louis, M. Tsai, C. Widjaja, J. Kanbar, J. Olvera, T. Tysl, L. Quezada, B. Boland, W. Huang, C. Murre, A. Goldrath, , J. Chang

The paper uses single-cell RNA sequencing to study CD8+ T cell differentiation during infection, revealing molecular determinants and functional heterogeneity in tissue-resident memory cells.

bioRxiv · Mar 2, 2020Immunology