Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics in a high-cholesterol diet mouse model
J. E. Joll, C. Clark, C. Scott…·W. D. Merryman
This study shows genetic ablation of Htr2b reduces hemodynamic indicators of aortic valve stenosis in a mouse model of CAVD, but pharmacological antagonism had no effect.