Author

W. Fitzsimmons

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. S. Lauring· 2 shared A. Avery· 1 shared A. Bhagwat· 1 shared A. French· 1 shared A. Woodman· 1 shared C. Arevalo· 1 shared C. Chen· 1 shared C. E. Cameron· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

A. S. Lauring

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vitro effect of a non-immunosuppressive FKBP ligand, FK1706, on SARS-CoV-2 replication in combination with antivirals

W. Fitzsimmons, T. L. Hartman, M. Mendenhall, C. Chen

The paper evaluates FK1706, a non-immunosuppressive FKBP ligand, in vitro against SARS-CoV-2 alone and in combination with remdesivir, showing synergistic activity.

bioRxiv · Feb 3, 2022 · PreprintPharmacology & Toxicology

Pre-existing immunity provides a barrier to airborne transmission of influenza viruses

S. Lakdawala, V. Le Sage, J. Jones, K. Kormuth, W. Fitzsimmons, E. Nturibi, G. Padovani, C. Arevalo, A. French, A. Avery, R. Manivanh, E. E. McGrady, A. Bhagwat, A. S. Lauring, S. E. Hensley

The paper shows that pre-existing non-neutralizing immunity in ferrets blocks airborne transmission of seasonal influenza viruses.

PLOS Pathogens · Feb 18, 2021Peer-reviewedMicrobiology

A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus

W. Fitzsimmons, R. J. Woods, J. T. McCrone, A. Woodman, J. J. Arnold, M. Yennawar, R. Evans, C. E. Cameron, A. S. Lauring

This study shows that RNA viruses evolve high mutation rates as a byproduct of selection for faster replication, not because of adaptive advantages.

bioRxiv · Apr 27, 2018Microbiology