A. Woodman

The paper investigates how imprecise recombinant viruses evolve through fitness-driven recombination and resolution processes, showing that resolution involves repeated recombination events leading to wild-type genomes.

This study investigates the factors influencing recombination in poliovirus, finding that genome function and fitness, rather than sequence identity or structure, determine the identity of recombinant progeny.

This study shows that a ribonucleotide analogue induces copy-back RNA synthesis, a new mechanism to combat RNA viruses by promoting defective viral genomes.

This study shows that RdRp speed and fidelity are not the only factors determining recombination efficiency in poliovirus, highlighting additional biochemical properties involved.

This study uses single-cell analysis to evaluate antiviral therapeutics, revealing efficacy and insights into drug resistance evolution and viral lifecycle impact.

This study shows that RNA viruses evolve high mutation rates as a byproduct of selection for faster replication, not because of adaptive advantages.