Author

W. Kastenmueller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. M. Mansilla· 1 shared A. Oener· 1 shared A. Zernecke-Madsen· 1 shared B. Ghesquiere· 1 shared B. S. Franklin· 1 shared C. Schmitt-Mabmunyo· 1 shared E. Latz· 1 shared G. Engels· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. M. Mansilla

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2 papers

Recent·Most cited

HIF-1α-mediated mitochondrial-glycolytic reprogramming controls the transition of precursor to terminally exhausted T cells

H. Wu, X. Zhao, S. M. Hochrein, M. Eckstein, G. F. Gubert, K. Knoepper, A. M. Mansilla, A. Oener, R. Doucet-Ladeveze, W. Schmitz, B. Ghesquiere, S. Theurich, J. Dudek, G. Gasteiger, A. Zernecke-Madsen, , M. Vaeth

This study identifies HIF-1α-mediated metabolic reprogramming as a mechanism controlling the transition of precursor T cells to terminally exhausted T cells in chronic infections and cancer.

bioRxiv · Aug 31, 2023 · PreprintImmunology

Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation

J. F. Rodrigues-Alcazar, M. A. Ataide, G. Engels, C. Schmitt-Mabmunyo, N. Garbi, W. Kastenmueller, E. Latz, B. S. Franklin

This study shows that Charcot-Leyden crystals activate the NLRP3 inflammasome, leading to IL-1β release and inflammation in vitro and in vivo.

bioRxiv · Jan 25, 2018Immunology