Author

N. Garbi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Organism:mouse· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Kurts· 2 shared E. Latz· 2 shared N. Kessler· 2 shared W. Kastenmueller· 2 shared A. Ablasser· 1 shared A. M. C. Boehner· 1 shared A. Odainic· 1 shared A. Roers· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

C. Kurts

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Author profile →

4 papers

Recent·Most cited

Opposing roles of resident and infiltrating immune cells in the defence against Legionella longbeachae via IL-18R/IFN-γ/ROS axis

L. M. Oberkircher, V. M. Scheiding, H. L. Rafeld, E. Hanssen, J. N. Hansen, M. J. Fleischmann, N. M. Kessler, D. Pitsch, D. Wachten, W. Kastenmueller, A. S. Brown, E. Hartland, I. R. van Driel, G. Z. Ng, N. Garbi

This study identifies opposing roles of tissue-resident alveolar macrophages and infiltrating neutrophils/monocyte-derived cells in controlling Legionella longbeachae infection via the IL-18R/IFN-γ/ROS pathway.

bioRxiv · Jan 31, 2024 · PreprintImmunology

Suppression of systemic T cell immunity to viral infection during liver injury is prevented by inhibition of interferon and IL-10 signaling

P. C. Hackstein, J. Spitzer, K. Symeonidis, H. Horvatic, T. Bedke, B. Steglich, L. Assmus, A. Odainic, N. Kessler, S. Klein, M. Beyer, R. Schmithausen, E. Latz, C. Kurts, J. Trebicka, , Z. Abdullah

The paper shows that liver injury suppresses systemic T cell immunity to viral infection, which can be reversed by inhibiting interferon and IL-10 signaling in preclinical models and human patients.

bioRxiv · Jul 21, 2022 · PreprintImmunology

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N. Kessler, S. F. Viehmann, C. Krollmann, K. Mai, K. M. Kirschner, H. Luksch, P. Kotagiri, A. M. C. Boehner, D. Huugen, C. C. de Oliveira Mann, S. Otten, S. A. I. Weiss, T. Zillinger, K. Dobrikova, D. E. Jenne, , N. Garbi

This study identifies cGAS/STING/IFN-mediated nucleic acid sensing by monocyte-derived macrophages as a driver of severe pulmonary vasculitis and shows that targeting this pathway reduces disease severity.

bioRxiv · May 30, 2022Immunology

Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation

J. F. Rodrigues-Alcazar, M. A. Ataide, G. Engels, C. Schmitt-Mabmunyo, N. Garbi, W. Kastenmueller, E. Latz, B. S. Franklin

This study shows that Charcot-Leyden crystals activate the NLRP3 inflammasome, leading to IL-1β release and inflammation in vitro and in vivo.

bioRxiv · Jan 25, 2018Immunology