Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury
W. Chen, W. Zai, J. Fan, X. Zhang, J. Luan, Y. Wang, Y. Shen, Z. Wang, S. Dai, S. Fang, D. Ju
This study shows IL-22 improves liver injury by promoting metabolic reprogramming and mitochondrial function through a signaling pathway involving AMPK, AKT, and mTOR.
bioRxiv · Jan 2, 2020Biochemistry