Author

W.-D. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Lischka· 1 shared B. M. Ghadimi· 1 shared C. Montagna· 1 shared D. Bronder· 1 shared D. Hirsch· 1 shared D. Wangsa· 1 shared E. Ruppin· 1 shared G. Auer· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Lischka

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2 papers

Recent·Most cited

Optical control of CRISPR-Cas editing with cyclically caged guide RNAs

Y.-J. Sun, J. Liu, J.-J. Li, Y. Zhang, W.-D. Chen, W.-Q. Cai, L. Liu, X.-J. Tang, J. Hou, M. Wang, L. Cheng

This paper introduces a method to control CRISPR-Cas gene editing using light-activated circular guide RNAs, enabling precise spatial and temporal gene editing in cells and embryos.

bioRxiv · Mar 4, 2022 · PreprintBiochemistry

Cancer-type specific aneuploidies hard-wire chromosome-wide gene expression patterns of their tissue of origin

N. Auslander, K. Heselmeyer-Haddad, S. Patkar, D. Hirsch, J. Camps, M. Brown, D. Bronder, W.-D. Chen, R. Lokanga, D. Wangsa, D. Wangsa, Y. Hu, A. Lischka, R. Braun, G. Emons, , t. ried

The paper shows cancer-type specific aneuploidies correlate with normal tissue gene expression patterns, suggesting they hard-wire chromosome-wide expression levels to support tumorigenesis.

bioRxiv · Mar 1, 2019Cancer Biology