Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
C. W. Schultz, Y. Zhang, R. Elmeskini, A. Zimmermann, H. Fu, Y. Murai, D. Wangsa, S. Kumar, N. Takahashi, D. Atkinson, L. K. Saha, C.-F. Lee, B. Elenbaas, P. Desai, R. Sebastian, , A. Thomas
This study shows that combining ATR inhibition with lurbinectedin improves efficacy in SCLC, particularly in MYC-driven non-neuroendocrine tumors.
EMBO Molecular Medicine · Aug 7, 2023Peer-reviewedCancer Biology
A. Prosz, H. Duan, V. Tisza, P. Sahgal, S. Topka, G. T.Klus, J. Borscok, Z. Sztupinszki, T. Hanlon, M. Diossy, L. Vizkeleti, D. R. Stormoen, I. Csabai, H. Pappot, J. Vijai, , Z. Szallasi
This paper identifies NER deficiency as a targetable vulnerability in ccRCC, showing that 10% of patients may respond to irofulven based on mutational signatures and PTGR1 expression.
bioRxiv · Feb 7, 2023Cancer Biology
K. Akagi, D. E. Symer, M. Mahmoud, B. Jiang, S. Goodwin, D. Wangsa, Z. Li, W. Xiao, J. D. Dunn, T. Ried, K. R. Coombes, F. J. Sedlazeck, M. L. Gillison
This study identifies heterocateny as a structural variation caused by HPV integration, promoting intratumoral heterogeneity and clonal evolution in oropharyngeal cancers.
bioRxiv · Aug 11, 2022Cancer Biology
D. Bronder, D. Wangsa, D. Zong, T. J. Meyer, R. Wardenaar, P. Minshall, A. Tighe, D. Hirsch, K. Heselmeyer-Haddad, L. Nelson, D. Spierings, J. C. McGrail, M. Cam, A. Nussenzweig, F. Foijer, , S. S. Taylor
This study shows that TP53 loss in fallopian tube epithelial cells drives chromosomal instability through cell cycle deregulation, without requiring additional mutations.
bioRxiv · Mar 12, 2021Cancer Biology
M. A. Brown, G. A. Dotson, S. Ronquist, G. Emons, I. Rajapakse, T. Ried
This study shows that TCF4 silencing alters chromatin structure and gene expression in colorectal cancer cells, identifying EMT and E2F pathways as deregulated and c-JUN as a key transcription factor.
bioRxiv · May 12, 2020 · PreprintCancer Biology
N. Auslander, K. Heselmeyer-Haddad, S. Patkar, D. Hirsch, J. Camps, M. Brown, D. Bronder, W.-D. Chen, R. Lokanga, D. Wangsa, D. Wangsa, Y. Hu, A. Lischka, R. Braun, G. Emons, , t. ried
The paper shows cancer-type specific aneuploidies correlate with normal tissue gene expression patterns, suggesting they hard-wire chromosome-wide expression levels to support tumorigenesis.
bioRxiv · Mar 1, 2019Cancer Biology
Z. M. Jowhar, S. Shachar, P. R. Gudla, D. Wangsa, E. Torres, J. L. Russ, G. Pegoraro, T. Ried, A. Raznahan, T. Misteli
This study investigates how variations in sex chromosome dosage affect chromosome organization in primary cells from SCA patients using HiCTMap imaging.
bioRxiv · Jun 13, 2018Cell Biology
Z. M. Jowhar, P. Gudla, S. Shachar, D. Wangsa, J. L. Russ, G. Pegoraro, T. Ried, A. Raznahan, T. Misteli
HiCTMap enables high-throughput imaging and analysis of chromosome territories in mammalian cells, providing precise 2D and 3D positioning and quantification.
bioRxiv · Sep 7, 2017Cell Biology
Y. Hu, J. Gaedcke, G. Emons, T. Beissbarth, M. Grade, P. Jo, M. Yeager, S. Chanock, H. Wolff, J. Camps, M. B. Ghadimi, T. Ried
This study identifies three colorectal cancer risk loci associated with poor prognosis in rectal cancer patients and links some SNPs to chemoradiotherapy resistance.
bioRxiv · Jun 30, 2017Cancer Biology