Pharmacology & ToxicologybioRxiv
Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)
X. G. Luong, S. K. Stevens, A. Jekle…·J. Deval
This study compares the efficacy of three THRβ agonists in modulating gene expression related to cholesterol and fatty acid metabolism in human and rat models.