Author

Y. Morales

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. B. Aldridge· 2 shared K. P. Davis· 2 shared A. L. McCabe· 1 shared B. Peters· 1 shared D. K. Hunt· 1 shared D. T. Hung· 1 shared E. A. Miller· 1 shared E. Hamami· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

B. B. Aldridge

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Massively parallel combination screen reveals small molecule sensitization of antibiotic-resistant Gram-negative ESKAPE pathogens

M. W. Tse, M. Zhu, B. Peters, E. Hamami, J. Chen, K. P. Davis, S. Nitz, J. Weller, T. Warrier, D. K. Hunt, Y. Morales, T. Kawate, J. L. Gaulin, J. H. Come, J. Hernandez-Bird, , P. C. Blainey

This study uses high-throughput screening to identify small molecules that enhance antibiotic efficacy against multidrug-resistant Gram-negative bacteria.

bioRxiv · Mar 26, 2024 · PreprintMicrobiology

NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni

M. Suresh Kumar Meena Kumari, P. Liu, K. Jump, Y. Morales, E. A. Miller, I. Shecter, M. J. Stadecker, P. Kalantari

This study identifies NLRP3 and AIM2 inflammasomes as key drivers of pathogenic Th17 responses in Schistosoma mansoni infection, showing their role in promoting inflammation and their counteraction by the IFN-I pathway.

bioRxiv · Mar 11, 2024 · PreprintImmunology

Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses

K. P. Davis, Y. Morales, A. L. McCabe, B. B. Aldridge, J. B. Mecsas

This study shows that antibiotic interactions vary with growth medium, with lung mimetic medium better predicting in vivo outcomes for Klebsiella pneumoniae.

bioRxiv · Sep 20, 2022Microbiology