Y. O. Alexandre

This study shows that SpiB regulates FRC network structure and CD8+ T cell responses in lymph nodes by affecting FRC function and immune coordination.

This study identifies fibroblastic reticular cells (FRCs) as essential for supporting lymph node-resident macrophages through CSF1 and CSF1R signaling.

This study shows that systemic inflammation during local infection suppresses lymphoid tissue remodeling and B cell immunity by causing lymphopenia and impairing dLN function.