Y. Suenaga

This study shows that liver-specific LXR inhibition reduces HDL levels and reverse cholesterol transport in cholesterol-fed mice by decreasing LXR-target gene expression.

This study identifies the CNH domain of NRK as a key mediator of cell death by localizing to the plasma membrane via phospholipid binding.

This study shows that inhibiting OCT4 binding at the MYCN locus in neuroblastoma cells reduces MYCN activity, leading to cell death through caspase-2 activation and downregulation of high-ORF dominance transcripts.

The paper measures ORF dominance in cancer and finds it increases with carcinogenesis, correlates with translation, and blurs coding/noncoding boundaries before metastasis.

This study introduces a PTI score to measure RNA coding potential and finds it correlates with translation and overlaps between coding and noncoding RNAs in different species.