ImmunologybioRxivPreprint
PTPN1/2 inhibition induces highly functional terminal effector CD8 T cells through autocrine IL-10
L. A. Perez-Quintero, A. Poirier, Z. Martinez-Cordoba…·M. L. Tremblay
This study shows that inhibiting PTPN1/2 enhances CD8 T cell effector function via autocrine IL-10, suggesting a new strategy for cancer immunotherapy.
DOI 10.1101/2023.04.17.537264