Author

Z. A. Shyr

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Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

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A. Ustione· 1 shared E. Egan· 1 shared M. S. Remedi· 1 shared Z. Yan· 1 shared

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2021-2021 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

A. Ustione

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintSep 17, 2021

SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes trough mitigation of oxidative and ER stress

Z. A. Shyr, Z. Yan, A. Ustione…·M. S. Remedi

This study shows SGLT2 inhibitors reduce oxidative and ER stress, restoring β-cell function in early-stage NDM mice but not when β-cell mass and identity are already lost.

DOI 10.1101/2021.09.17.460837

mouseexperimental assay

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