Cancer BiologybioRxiv
In Vivo CRISPR Screens Identify E3 Ligase Cop1 as a Modulator of Macrophage Infiltration and Cancer Immunotherapy Target
X. Wang, C. Tokheim, B. Wang…·X. S. Liu
The paper identifies Cop1 as a modulator of macrophage infiltration and cancer immunotherapy in TNBC by using in vivo CRISPR screens and multi-omics analyses.
DOI 10.1016/j.cell.2021.09.006