Herbert Y. Gaisano

This study shows that GSDMD pore formation stops caspase-4 activity to control IL-18 production in intestinal epithelial cells, preventing excessive inflammation.

This study shows that bacterial ADP-heptose triggers a revival stem cell program in the intestinal epithelium by inducing Paneth cell dedifferentiation and ISC loss.

This study shows that neuronal SNAP-23 is essential for hippocampal synaptic plasticity and spatial memory but not for basal glutamate receptor function.