Fei Huang

This study investigates the distinct roles of hypusinated and unhypusinated eIF5A isoforms in pancreas development and function using zebrafish and mouse models.

This study shows that inhibiting PERK reduces autoimmune diabetes risk in mice by decreasing β cell immunogenicity and improving islet function.

This study identifies PTPN2 as a therapeutic target in AML, discovers a selective inhibitor K73, and demonstrates its efficacy in reducing AML burden in vitro and in vivo.