Author
University of Wisconsin–MadisonORCID 0000-0001-6990-2668Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Julia C. Colwell, John P. Maufort, Kathryn M Williams…·Jenna Kropp Schmidt
This paper describes a reproducible method to generate rhesus macaque induced pluripotent stem cells (RhiPSCs) from MAPT R406W carriers for in vitro modeling of frontotemporal dementia.
Ludwig A. P. Metzler, Jeanette M. Metzger, Keenan Gerred…·Amita Kapoor
This study measures blood biomarkers of neurodegeneration and inflammation in rhesus macaques across adulthood, finding age-related increases in NfL and IL-6 and a decline in Aβ42/Aβ40 ratio.
Samuel S. Neuman, Jeanette M. Metzger, Viktoriya Bondarenko…·Marina E. Emborg
The paper shows that genome editing in the striatum leads to fluorescent reporter expression in the substantia nigra pars reticulata via anterograde axonal transport.
Jeanette M. Metzger, Yuyuan Wang, Samuel S. Neuman…·Shaoqin Gong
This study develops non-viral nanocapsules for in vivo CRISPR-Cas9 delivery to edit neuronal DNA in mice, achieving efficient and safe genome editing in specific neuron types.