Ryan V. Moriarty

This study identifies a tissue virus microenvironment with stress responses that supports SIV persistence, contrasting with transient reservoirs that show immune activity.

This study shows CD8α+ cells suppress SIV replication without immune escape in post-treatment controllers, using a macaque model and barcoded viral sequencing.

This study shows that potent antibody-dependent cellular cytotoxicity (ADCC) by a V2-specific antibody is insufficient to protect macaques against SIV challenge, but reduced viral loads were observed with a neutralization-sensitive SIV variant.

The paper constructs six-species synthetic yeast hybrids and shows they are chromosomally unstable but can rapidly adapt to novel environments.

The paper shows that the mitochondrial genome origin determines temperature tolerance in lager-brewing yeast hybrids.