Multiviral RBD-decorated chimpanzee adenoviral vaccine elicits broad neutralizing immunity against diverse betacoronaviruses
Bethany G. Charlton, Rosa D'Agostino, Rebecca A Russell…·Matthew D. J. Dicks
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University of OxfordORCID 0000-0001-8507-7282Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Bethany G. Charlton, Rosa D'Agostino, Rebecca A Russell…·Matthew D. J. Dicks
Zhenyu Li, Matthew D. J. Dicks, Louisa M. Rose…·Dan H. Barouch
This study shows that displaying an antigen on adenovirus capsids and encoding it as a transgene enhances both humoral and cellular immune responses in rhesus macaques.
Rebecca A Russell, James B. Lok, James Michael Harris…·Matthew D. J. Dicks
This study develops a vaccine using PreS1-decorated adenovirus that induces neutralizing antibodies and T-cell responses against HBV and HDV.
Lloyd D. W. King, David Pulido, Jordan R. Barrett…·Simon J. Draper
This paper develops a stabilized RH5 VLP vaccine that induces improved anti-malarial antibodies compared to a soluble protein vaccine in preclinical studies.