Thomas G. Graeber

This study shows Coenzyme A enhances alternative macrophage activation via MyD88-linked signaling by providing a weak TLR4 signal.

This paper develops a radio-theranostic approach targeting LRRC15 to image and treat cancer, showing tumor reduction and reversal of immunotherapy resistance.

This study identifies metabolic vulnerabilities in glioblastomas driven by TERT and shows that combining GCLC and glutamine-utilizing enzyme inhibitors synergistically targets these vulnerabilities.

This study reprograms AR-active prostate cancer to NEPC using ASCL1 and NeuroD1, revealing their role in silencing AR and altering chromatin structure.

The paper shows MITF promotes melanoma survival by increasing resistance to reactive oxygen species through regulating antioxidant genes like IDH1 and NNT.