Marie‐Pier Tétreault

This study shows that deleting epithelial Ikkβ in mice delays early esophageal carcinogenesis by reducing inflammation, T cell recruitment, and IFNγ/CXCL9 signaling.

This study shows that deleting Ikkβ in esophageal epithelial cells worsens eosinophilic esophagitis in a mouse model, highlighting the importance of IKKβ/NFκB signaling in preventing allergic inflammation.

The paper investigates autophagy's role in esophageal homeostasis, finding that high autophagic vesicle content in basal cells correlates with limited proliferation and enhanced self-renewal.

The paper identifies a systemic age-dependent transcriptome imbalance driven by transcript length across multiple species and shows its correlation with splicing factors and environmental stressors.

This study uses single-cell RNA sequencing to identify cellular diversity and age-related mitochondrial dysfunction in murine esophageal epithelium.