Author

Zhi Hua Yang

Brigham and Women's HospitalORCID 0000-0001-9440-7896Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Fengfeng BeiiD· 1 shared Jun PuiD· 1 shared Kai HuangiD· 1 shared Shanrui Pu· 1 shared Shiyi QiniD· 1 shared Victoria J. MadiganiD· 1 shared Xi Chen· 1 shared Xianqun FaniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperBioengineering

Fengfeng BeiORCID

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2 papers

Recent·Most cited

BioengineeringCell Reports MedicinePeer-reviewedMay 22, 2025

Tropism of AAV.CPP.16 in the respiratory tract and its application for a CRISPR-based gene therapy against SARS-CoV-2

Zhi Hua Yang, Yizheng Yao, Xi Chen…·Fengfeng Bei

This study evaluates AAV.CPP.16 as a gene delivery vector for respiratory diseases and demonstrates its use in a CRISPR-based therapy targeting SARS-CoV-2.

4 citations

mousenon-human primate

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BiophysicsbioRxivPreprintFeb 5, 2024

Scaling laws of molecular residence time

Shiyi Qin, Zhi Hua Yang, Kai Huang

The paper reveals power law residence scaling in both passive and active liquids, showing sensitivity to liquid environment and suggesting active phase separation as a scaling proofreading mechanism in gene regulation.

DOI 10.1101/2024.02.05.578884

statistical modelmechanistic / dynamical model

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