Fengfeng Bei

This study shows that OPTN dysfunction leads to neuroinflammation and RGC death in glaucoma, independent of IOP, and identifies OPTN-NPY signaling as a potential therapeutic target.

This study evaluates AAV.CPP.16 as a gene delivery vector for respiratory diseases and demonstrates its use in a CRISPR-based therapy targeting SARS-CoV-2.

This paper develops a high-throughput BTB assembloid model to study glioblastoma-neurovascular interactions and therapeutic responses, finding that BTB disruption correlates with increased tumor invasiveness and drug resistance.