Midori Ishii

This study shows that the KKT2 CL domain binds histone H3 N-terminus and that methylation of this region disrupts binding, suggesting a mechanism for kinetochore assembly in kinetoplastids.

This study identifies 17 proteins localized to the feeding apparatus and flagellar apparatus in Diplonema papillatum, providing foundational insights into their molecular mechanisms.

This study determines the structure and function of KKT23, a kinetochore acetyltransferase in trypanosomes, showing it acetylates histone H2A and interacts with KKT22.

This study shows that Aurora B and KKT14 form an unconventional regulatory pathway controlling mitotic exit and chromosome segregation in trypanosomes.

This study identifies KKT14-KKT15 in kinetoplastids as divergent orthologs of Bub1/BubR1-Bub3, suggesting a unique mechanism for chromosome segregation fidelity in trypanosomes.