Author

Ryland D. Mortlock

National Institutes of HealthORCID 0000-0001-9666-4394Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Cell Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:rat· 2 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:multiple species· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Chuanfeng WuiD· 2 shared Cynthia E. DunbariD· 2 shared Aisha A. AljanahiiD· 1 shared Ashley Laurel Gin· 1 shared Byung‐Chul LeeiD· 1 shared Diana M. AbrahamiD· 1 shared Diego A. EspinozaiD· 1 shared Komudi SinghiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Chuanfeng WuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologyCell stem cellPeer-reviewedMar 19, 2024

Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques

Byung‐Chul Lee, Ashley Laurel Gin, Chuanfeng Wu…·Cynthia E. Dunbar

This study compares CRISPR/HDR and lentiviral transduction effects on HSPC engraftment and clonal dynamics in rhesus macaques, finding HDR-edited cells decline rapidly while lentiviral cells persist longer.

31 citations

ratexperimental assay

𝕏 PostBluesky

BioinformaticsNature Computational SciencePeer-reviewedApr 26, 2021

barcodetrackR: an R package for the interrogation of clonal tracking data

Diego A. Espinoza, Ryland D. Mortlock, Samson Koelle…·Cynthia E. Dunbar

barcodetrackR provides tools for analyzing clonal tracking data to study lineage reconstitution and clonal dynamics in gene and cell therapy studies.

21 citations

humanmultiple species

𝕏 PostBluesky

Systems BiologyCellular and Molecular BioengineeringPeer-reviewedSep 8, 2020

Dynamic regulation of JAK-STAT signaling through the prolactin receptor predicted by computational modeling

Ryland D. Mortlock, Senta K. Georgia, Stacey D. Finley

The paper develops a computational model of JAK-STAT signaling through the prolactin receptor in beta cells, showing that receptor upregulation and regulatory modules are needed to match experimental STAT5 dynamics.

19 citations

ratstatistical model

𝕏 PostBluesky