Author

Shelby R. Madden

Oregon Health & Science UniversityORCID 0000-0001-9713-4803Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

David A. ConstantiD· 2 shared Timothy J. NiceiD· 2 shared Alec M. GriffithiD· 1 shared Alexis R. GibsoniD· 1 shared Austin P. WrightiD· 1 shared Bryan Ramirez Reyes· 1 shared Ethan Mulamula· 1 shared Gargi MishraiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

David A. ConstantORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 25, 2025

Plasmacytoid dendritic cells in the intestine preferentially produce interferon lambda at homeostasis contributing to tonic localized innate immune responses

David A. Constant, Jacob A. Van Winkle, Philip A Norwood…·Timothy J. Nice

This study identifies intestinal plasmacytoid dendritic cells (pDC) as a major source of homeostatic IFN-λ and shows TGF-β regulates their IFN production.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyMucosal ImmunologyPeer-reviewedApr 9, 2024

Interferon Regulatory Factor 6 Determines Intestinal Epithelial Cell Development and Immunity

Austin P. Wright, Sydney Harris, Shelby R. Madden…·Timothy J. Nice

This study identifies IRF6's role in regulating intestinal epithelial cell development and innate immunity, showing it modulates antiviral responses and maintains barrier function.

14 citations

mousescRNA-seq

𝕏 PostBluesky