Rose Zamoyska

This study identifies shared cell cycle control mechanisms between CD8 T cells and embryonic stem cells, revealing similarities in cyclin expression and Emi1 function that support rapid proliferation.

This study shows that deleting PTPN22 in T cells enhances initial anti-tumor effector function but accelerates T cell exhaustion, with TIM-3 expression linked to IL-2 signaling and NFIL3.

This study shows that eIF5a modification regulates protein translation in CD8 T cells, affecting cytokine production and cell cycle control during activation.