Koshiro Tabata

This study uses cryo-ET to analyze native, active SARS-CoV-2 virions, revealing a transient open-trimer prefusion state and hidden spike flexibility with implications for vaccine design.

This study shows favipiravir suppresses OROV replication and disease in hamsters, preventing neuroinvasion and pathogenic host responses through transcriptomic analysis.

This paper shows that WNV capsid protein causes nuclear deformation via PKCα-dependent lamin phosphorylation, which supports viral replication and disease.

This study evaluates AddaS03 as an adjuvant for a WNV subunit vaccine, showing it elicits higher neutralizing antibody titers and provides full protection in mice compared to Alhydrogel.

This paper develops a CPER-based reverse genetics system for rabies virus, enabling the generation of recombinant viruses with various genetic modifications.

This study establishes a lethal mouse model of Oz virus infection, revealing hepatic involvement and demonstrating the efficacy of antiviral drugs and vaccines against the virus.

The paper compares TMUV cluster 1 and 2 strains, finding cluster 2 has higher replication efficiency in human cells and induces stronger innate immune responses.